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  • When this Center’s funding ended in 2013, researchers were developing and testing cell- and gene-based approaches to correct the molecular defects underlying Duchenne muscular dystrophy., Partner institution:, University of Wisconsin-Madison
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  • When this Center’s funding ended in 2009, researchers were developing cell- and gene-based approaches to correct the molecular defects underlying Duchenne muscular dystrophy and limb-girdle muscular dystrophies.
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  • URL: http://www.umassmed.edu/wellstone/cores/ External Website Policy external link, The University of Massachusetts Wellstone Center maintains a repository of biomaterials collected from facioscapulohumeral muscular dystrophy patients and unaffected relatives. It can provide characterized facioscapulohumeral muscular dystrophy cells and control muscle cells to labs studying facioscapulohumeral muscular dystrophy or other muscular dystrophies.
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  • The University of Iowa Wellstone Center maintains a national tissue and cell culture resource for research, and a laboratory for patient diagnostic and post-intervention biopsy evaluation for clinical trials.
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  • URL: http://www.utsouthwestern.edu/research/wellstone/cores/myoediting/ External Website Policy external link, The UT Southwestern Wellstone Center is establishing a comprehensive electronic database that will optimize exon-skipping strategies to rescue of dystropin expression in iPSC-derived muscle cells.
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  • URL: https://www.urmc.rochester.edu/neurology/national-registry/ External Website Policy external link, The University of Rochester Wellstone Center maintains a registry of more than 2,100 patients with myotonic dystrophy and patients with facioscapulohumeral muscular dystrophy. Researchers can apply to the Registry’s Scientific Advisory Committee to access deidentified data or to obtain assistance with patient recruitment.
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  • URL: http://myology.institute.ufl.edu/shared-resource-core/ External Website Policy external link, The University of Florida Wellstone Center performs ex vivo, in situ, and whole animal assessments of muscle integrity and function for mouse studies of potential muscular dystrophy therapies. This core serves as a national resource for performing functional evaluation of potential therapies for the muscular dystrophies.
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  • URL: http://depts.washington.edu/mdcrc/vector_core.html External Website Policy external link, The University of Washington Wellstone Center provides viral and plasmid vectors for studies in small and large animal models. Services offered by the Core include consulting, reagents and training related to vector production.
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  • Wellstone Muscular Dystrophy Research Centers Meeting (November 2019) - Overview Presentations, Video of Overview Presentations External Website Policy external link, Evaluation of the Paul D. Wellstone Muscular Dystrophy Research Centers (January 2019), Executive Summary, Wellstone Center Workshop and Conference Reports, Experimental protocols for DMD animal models External Website Policy external link (based on 2007 and 2008 workshops co-funded by TREAT-NMD and the Foundation to Eradicate Duchenne, Inc.)
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  • The Centers of Excellence program in muscular dystrophy research was established by NIH in 2003, in honor of the late Senator Paul D. Wellstone of Minnesota. Established as part of the NIH enhancement and intensification of muscular dystrophy research associated with the MD-CARE Act, the centers are supported by five-year, renewable grants. The following NIH Institutes participate in the…, Eunice Kennedy Shriver, National Institute of Child Health & Human Development (NICHD) National Institute of Neurological Disorders and Stroke (NINDS) National Heart, Lung and Blood Institute (NHLBI) Each Center involves several research projects and core facilities with an emphasis on translational and clinical research for various muscular dystrophies. Each Center has at least one core facility that shares its…
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